1846 Spends fifteen months at a water-cure spa in Brattleboro, Vermont, where her health, weakened after bearing five children in ten years, is restored.
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1848 Calvin Stowe spends fifteen months at the Brattleboro water cure.
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1849 Samuel Charles Stowe is born and dies during a cholera epidemic. This death deeply affects Harriet Beecher Stowe. Calvin Stowe accepts a position as Professor of Natural and Revealed Religion at Bowdoin College, his alma mater, in Brunswick, Maine, and the family moves there in 1850.
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1850 The Fugitive Slave Act is passed, making it possible for slaves to be hunted throughout the United States and containing inadequate protection for free blacks. Harriet Beecher Stowe vows to write about the evils of slavery. Begins to publish stories in the National Era, an abolitionist paper in Washington, D.C. Reads the novels of Sir Walter Scott and Charles Dickens aloud to her children. Charles Edward Stowe is born.
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1851 Uncle Tom's Cabin; or, Life among the Lowly, her first novel, is published in installments in the National Era.
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1852 Uncle Tom's Cabin appears as a book, published by J.P. Jewett in Boston, selling an unprecedented 3,000 copies the first day and 300,000 copies the first year. Receiving a royalty of 10 percent, Harriet Beecher Stowe earns $10,000 in the first four months of the novel's publication, although she lost a fortune by declining to enter a joint venture that would have split the costs and profits with the publisher. Stowe family moves to Andover, Massachusetts, where Calvin becomes Professor of Sacred Literature at Andover Theological Seminary.
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185260 Uncle Tom's Cabin is reprinted in twenty-two different languages ranging from Armenian to Welsh, becoming the world's second most popular book, second only to the Bible.
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