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incontinence. Decreased glomerular filtration rate.
Endocrine
Altered temperature and swearing responses, circadian
rhythm, regulation of hormones, and impaired
glucose intolerance.
Musculoskeletal
Muscle: increased muscle weakness (especially in
antigraviry muscles), atrophy, risk of contracture,
weakened myotendinous junction, and altered muscle
excitation. Bone: osteoporosis. Joints: degeneration
of cartilage, synovial atrophy, and ankylosis,
Neurologic
Sensory and sleep deprivation. Decreased balance,
coordination, and visual acuiry. Increased risk of
compression neuropathy.
Neurovascular
Orthostatic hyporension.
Body composition
Increased calcium, potassium, phosphorus, sulfur, and
nitrogen loss; increased body fat and decreased lean
body mass.
Vozmax = maximum oxygen uptake.
Source: Adapted from RM Buschbacher, CD Porter. Decondirioning, Conditioning, and
the Benefits of Exercise, In RL Braddom (ed), Physical Medicine and Rehabilitation
(2nd ed). Philadelphia: W.B. Saunders, 2000;704.
APPENDIX [-B: AClITE CARE SEITING
755
tions, medical-surgical prognosis, and quality of life as well as personal values and beliefs.' End-of-life issues facing patients, family, and caregivers include the following:
Decisioll to Declare Resuscitatioll Status as Do Not Resuscitate
or Do Not bltl/bate
Do 1I0t resuscitate (DNR) is the predetermined decision to decline cardiopulmonary resuscitation, including defibrillation and pharmacologic cardioversion in case of cardiorespiratory arrest. Do not intubate (DNl)
is the predetermined decision to decline intubation for the purpose of
sub equem mechanical ventilation in case of respiratOry arrest. DNR or
DNl status is officially documented in the medical record by the attending physician. The physical therapist must be aware of each patient's resuscitation or "code" status. DNRlDNI orders do nOt directly impact
on the physical therapy plan of care.
Withholdillg alld Withdrawillg Medical Therapies
Withholdillg sup/lort is not initiating a therapy for the patient,
whereas withdrawillg sup/lort is the discontinuation of a therapy
(usually after it has proven un beneficial to the patient).6 Forgoillg
therapy is the combination of withholding and withdrawing suppOrt
in which disease progression is allowed to take its course.6 In the case
of forgoing medical-surgical therapies, an order for "comfort measures only" (CMO) is written by the physician. The patient with comfort measures only status receives medications for pain control or sedation, or to otherwise eliminate distress. The patient on comfort
measures only status does not receive physical therapy.
Collta, Persistellt Vegetative State, alld Brain Death
The diagnosis of coma, persistent vegetative state, or brain death can be
devastating. These conditions are very similar in that there is unconsciousness and absent self-awareness, bur distinctions do exist in terms of neurologic function and recovery (Table I-B.2). Coma is characterized by a lack of responsiveness to verbal stimuli, variable responsiveness to painful stimuli, voluntary movement, and the potential for abnormal respiratory patterns and pupillary responses to light.7 Characteristics of /lersistellt vegetative state include the presence of sleep-
Table I-B.2. Comparison of Coma, Persistent Vegetative State (PVS), and Brain Death
'-'
'"
'"
Sleep-Wake
Respiratory
Cerebral
Condition
Cycle
Moror Control
Control
EEG Activity
Metabolism
Prognosis
g '"
Coma
Absent
Lacks
Present, vari-
Present
Reduced by
Usually recovers.
�
'"
purposeful
able, usually
50% or more
Can progress to
'"
movement
depressed
PVS or death in
J:
�
2-4 wks.
o
PVS
Present
Lacks
Present, normal
Present
Reduced by
g
purposeful
50% or more
Variable recovery.
"
movement
Cl
'"
Brain death
Absent
None or spinal
Absent
Absent
Absent
No recovery.
i
reflex move-
;;j
ments only
r;!
r
EEG electroencephalogram.
:i!
=
Source: Adaprcd from LA Thclan. LD Urden, ME Lough, Kt"1 Stacy (eds). Neurological Disorders. In Critical Care Nursing: Diagnosis and
�
>
Management (3rd ed). St. Louis: Mosby, 1998;797.
�
APPENDIX 1-8: AClITE CARE SETIlNG 757
wake cycles and partial or complete hypothalamic and autonomic
brain stem functions but a lack of cerebral cortical function for longer
than I momh afrer acute traumatic or nontraumatic brain injury or
metabolic or degenerative disorders.s The initial clinical criteria for
brain death include coma and unresponsiveness, absence of brain stem
reflexes, and cerebral motor responses to pain in all extremities, apnea,
and hypothermia.' Brain death is usually confirmed by cerebral angiography, evoked potential testing, electroencephalography, or transcranial Doppler sonography.' Refer to Chapter 4 for more information on
these neurologic diagnostic tests.
Intensive Care Unit Setting
The ICU, as its name suggests, is a place of intensive medical-surgical
care for those patients who require continuous monitoring, usually in
conjunction with thcrapies such as vasoactive medications, sedation, circulatory assist devices, and mechanical ventilation. ICUs may be named according to the specialized care that they provide, such as the coronary
care unit (CCU) or surgical ICU. The patient in the ICU requires a high
acuity of care; thus, the nurse to patient racio is onc to one or one to two.
Com mOil Patiellt and Family Respo1tses to the /lIte1tsiue Care Ullit
• Behavioral changes or disturbances can occur in the patient who
is critically ill as a result of distress caused by physically or psychologically invasive, communication-impairing, or movement-restricting procedures.'o When combined with the environmental and psychological reactions to the ICU, mental status and personality
can be altered. Environmental stresses can include crowding, bright
overhead lighting, strong odors, noise, and touch associated with
procedures or from those the patient cannot see.IO Psychological
stresses can include diminished dignity and self-esteem, powerlessness, vulnerability, fear, an.xiety, isolation, and spiritual distress. 10
• ICU psychosis is a state of delirium that occurs between the third
and seventh day in the ICU and is described as a "fluctuating state of
consciousness characterized by features such as fatigue, confusion,
distraction, anxiety, and hallucinations." II Delirium in the leU,
which is reversible, is thought to be caused by pain, the side effects
of drugs, and the ICU environment." Precipitants to delirium