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770 AClITE CARE HANDBOOK FOR PIIYSICAL TIIERAI'ISTS
Oxygen Therapy
The general indication for 0, therapy is hypoxemia. Hypoxemia is
considered to be present when the arterial oxyhemoglobin saturation
(Sao,) is less than 90%, corresponding to an arterial blood 0, partial
pressure (Pao,) of less than 60 mm Hg.' Refer to Table 2-4 for the relation between 0, saturation as measured by pulse oximetry (Spo,) and Pao, and to Figure 2-7 for the oxyhemoglobin dissociation curve. The
goal of 0, therapy is to treat and prevent hypoxemia, excessive work
of breathing, and excessive myocardial work by increasing the Pao,.3
0, moves across the alveolar-capillary membrane by diffus-ioll,
the physiologic mechanism by which gas moves across a membrane from a region of higher to lower pressure and is driven by the partial pressure gradient of 0, between alveolar air (Pao,) and
pulmonary capillary blood. To improve diffusion, a rise in I'ao,
can be attained by increasing the fraction of inspired 0, IFio,)
with supplemental 0,'
Supplemental 0, is delivered by variable performance ITable lIl
A.l) or fixed performance (Table IlI-A.2) systems. Each cannula or
mask is designed to provide a range of Fio,. A variable performance
system should not be used if a specific Fio, is required. Variable performance systems are nOt intended to meet the total inspiratory requirements of the patient. The actual Fioz for a given flow rate in a
variable system is dependent on a patient's tidal volume and respiratory rate, and the type, fit, and placement of the cannula or mask. If a specific Fio, is required, then a fixed performance system is indicated.
Fixed performance systems deliver a specific Fio, despite the patient's
respiratory rate and pattern.4
0, delivery devices with masks or reservoirs allow 0, to collect
about the nose and mouth during exhalation, which increases the availability of 0, during inhalation. As the storage capacity of the mask or reservoir is increased, the Fioz for a given flow rate is also increased.s
The supplemental 02 requirements of a patient may fluctuate with
activity. Monitoring Sao, with pulse oximetry (identified as Spo,) and
subsequent titration (weaning) of 0, may be indicated during exercise. The physician may order parameters for resting and exercise Spo, if a patient has a low activity tolerance or an abnormally low
Spo, at baseline.
A patient with chronic obstructive pulmonary disease who has
chronic carbon dioxide retention may become desensitized to the
respiratory stimulant effects of carbon dioxide. In these patients,
ventilation is driven by means of a reflex ventilatory response ro a
Table lIJ-A.l. Variable Performance Oxygen Delivery""
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DeviceIFio1
Description
Clinical Implications
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X
Nasal cannula
Purpose: delivers supplemental 02 mixed
•
The rule of thumb for the cannula system is that Fio., is
T
?=
RA::::: 21 % Fio1,
with RA, usually 1-6 Ipm. The maxiincreased by 3-4% for each Iprn of °2,
-
l::
1 Ipm::::: 24% Fio2,
mum is 8 lpm.
m
•
Mouth breathing does not necessarily indicate that a
"
2 Ipm ::::: 28% Fio"
Consists of: prongs, which are attached
patient is nO[ receiving supplemental 0"
g
3 Ipm::::: 32% Fio;,
ro an 0, source via small-bore plastic
•
If nasal passages are obstructed, 0., is able to colleer in
J:
4 Ipm
c
� 36% Fio"
tubing a-nd are positioned in the
the oral and nasal cavities and is d;awn in on
::;
5 Ipm::::: 40% Fio2,
patient's nose. The tubing is secured by
inspiration.
6 Ipm
g
::::: 44% Fiol
placing it behind the patient's ears and
•
Flow rates of greater than 8 Jpm are unlikely [0 increase
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under the patient's chin (Figure
delivered 02 further and may prove uncomfortable and
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lead to mucosa desiccation.
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Provide mobile patienrs with adequate lengths of
extension tubing or a portable 01 rank to enable
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functional mobility. Patients should be instructed to
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avoid tripping over or becoming tangled in the tubing.
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The tubing may lead CO irritation or skin breakdown
behind the ears of some patients. Sofr gauze padding
may be placed around the rubing to protect the patient's
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skin.
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