The Magic Bullet (27 page)

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Authors: Harry Stein

BOOK: The Magic Bullet
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Suddenly Shein burst out laughing. “That’s not bad, I gotta try it myself sometime!” He took off his glasses and wiped his eyes with his sleeve. “God, Logan, you must feel like a fuckin’ jerk!”

“There was no way I could’ve caught it, they didn’t send the paperwork.”

“You examined her, didn’t you? You got eyes and ears, don’t you?” He laughed again. “Ah, it’s no big deal. Learn from it.”

“Learn
what
—that people’ll screw around with your work?”

“In small ways? Sure, all the time.” He picked up his fork and held it, poised in midair. “Lighten up, Logan. This is a tough business, get used to it.”

“Do you hear me complaining?”

“I don’t have to hear the words.” He jabbed a forkful of macaroni and cheese into his mouth. “In my book, this falls into the ‘acceptable’ category. They pushed you into a rookie’s mistake—but there’s no lasting damage.”

Logan, insides churning, hoped he looked half as calm as Shein.
Mistake? What the hell was he talking about now?

“You were just a little too eager to stick it to Stillman, weren’t you?” noted Shein. “So maybe you let down your guard a little with Mrs.… what’s her name?”

“Faith Byrne.”

“In your mind, she became a prize catch. You wanted her so bad, you were ready to suspend good judgment.” He paused, took another bite. “Stillman can’t read people like I can, but he’ll beat an amateur any day of the week.”

Logan had entertained the vague hope that Shein would help him find a way out of this; maybe tell him a way he might have Byrne replaced on the protocol by a less troublesome patient; or, at the very least, arrange to have Marion Winston kept at a greater distance from the program.
But it was clear now that none of that was going to happen.

“Well,” he said blithely, turning away, “just thought you’d want to know.”

“Hey, Logan, wait a sec.”

The younger man turned, surprised by the new note in Shein’s tone—something uncannily like sympathy. “Yes?”

“I just wanna tell you: Hang in there, you’re a good man.”

As he walked off, Logan, once again, didn’t know whether he’d just been flattered or humiliated.

The surest solace, of course, was in the work, and fortunately there was more than enough of it to keep Logan from dwelling on very much else. The next ten days proved particularly arduous. New patients were now being eased onto the protocol at the accelerated rate of three per week, which meant that in short order fifteen women would be receiving Compound J. Already, half the protocol patients were reporting to the ACF semiweekly on an outpatient basis, arriving after lunch and remaining until early evening. Though the actual administration of the drug took less than an hour, each visit also included a thorough examination (including the taking of blood samples and X rays) and a consultation with one of the three young physicians supervising the protocol.

On top of which, Logan, Sabrina, and Reston had their obligations at the hospital.

Under the circumstances, their workdays often continued past midnight—with conversations about the protocol usually left for last. Thus it was that one Thursday night the phone rang in Logan’s place just as he was turning off David Letterman: Sabrina needed to compare notes on a patient named Sharon Williams. A black schoolteacher from Baltimore, thirty-eight and married, Williams seemed a promising candidate. But there was something about the case that bothered Sabrina. Her cancer had been diagnosed
following a long siege of back pain, tests having revealed a malignant lesion in the fourth lumbar vertebra.

“It is a very interesting case,” noted Sabrina. “The problem is that it’s in the bone—she has no lumps. This will make it hard for us to measure changes in the tumor.”

“That’s true,” he agreed. In fact, in such a malignancy, tumors are seen only as shadows on a bone scan—and these can remain for months even if a drug is working.

“One must ask: What is the point to have a patient on the protocol if we can’t see the results?”

It was a valid question, and hearing Sabrina raise it, Logan realized how much more pragmatic she’d grown in the several months they’d been at this. “You’re right. Especially since we have only one place left.”

She hesitated. “Still, I found her a lovely woman.”

“I know,” he conceded. “So did I.”

“Who knows,” she began arguing with herself, “maybe it is wrong to see the bone malignancy just as a problem. Why not look at it as an opportunity? This is a different form of breast malignancy, a different kind of test for the drug.”

“That could be. I think—”

Abruptly, there came a beep on her end of the line—call waiting.

“Who could it be at this hour?” she wondered. “Hold a second, Logan.”

A moment later she was back. “I must take this. It is Marion Winston. Something has happened to Judith Novick. I will call you back.”

Logan’s wait was probably less than three minutes, but it felt like a decade.

“What is it?” he demanded, snatching up the phone before the end of the first ring.

“It is terrible news. She had a bad fall.”


How
bad?”

“A fractured skull. She is in a coma.”

“Where is she?”

“At Bedford General Hospital. In Pennsylvania, where she lives.”

Logan was numb. “What’s Winston doing in the middle of it?”

Sabrina knew better than anyone how sensitive the topic was. “She is the patient care representative, Dan,” she said gently. “Her family gave the hospital her name.”

But beyond shock, concern, and empathy, both of them were already starting to think about something else: the impact on the protocol. Which was only part of why Logan found himself irked that Winston hadn’t seen fit to notify him, the head of the Compound J team.

“I think I should call her husband,” said Sabrina suddenly.

“At this hour?”

“Winston says she just talked to him. He is at the hospital.”

“Tell him how much we’re all pulling for her.”

“Yes. Of course.”

Thirty seconds later, Logan had Winston on the line.

He could almost see her stiffen at the sound of his voice. “Dr. Logan, it’s late. I’ve already passed on all the pertinent information to Dr. Como.”

“Please bear with me, I just have a few more questions. Can you tell me exactly what happened?”

“She fell. That’s all we know.”

“At home?”

“No, it was at a mall.”

“A mall?”

“On some steps by the parking lot.”

“Jesus,” he exclaimed softly.
What the hell was WRONG with her, shopping at that hour? Her balance was off! Shit, I WARNED her to take it easy!

“Is that all, Doctor? Think you’ll be able to save your protocol?”

Logan ignored the unmistakable note of contempt. “Ms. Winston, my primary concern is her condition.”

“No, I think your primary concern is keeping her on
the protocol. But, obviously, that is now out of the question.”

“Of course.” Even if such a thing were plausible medically, it would be unthinkable to continue dosing a comatose patient. “I’ll be keeping close tabs on her condition. Perhaps if she recovers soon enough—”

“I meant
permanently
out of the question.”

Since the matter was almost entirely theoretical, Logan was surprised by the adamant nature of the response. “Why? She seems to have had some response to the drug already.”

“Because, Doctor, some of us don’t take those kinds of risks. We don’t know what happened to Mrs. Novick—but it could be your drug caused her to black out.” She paused, letting it sink in. “In my view, this must be regarded as a possible drug-related toxicity.”

The next morning, in Shein’s office, Logan didn’t bother with the niceties. “Something has to be done about Marion Winston,” he announced flatly. “The woman’s hostility toward this protocol is pathological.”

Shein stared at him evenly across his cluttered desk. “Toward the protocol or toward you?”

“Both. It doesn’t matter, the result’s the same. Can you believe it, she’s going to try to pass this off as a toxicity problem?”

When Shein made no response, he pressed on. “That’s bullshit and you know it! The odds are one in a thousand that the drug had anything to do with it.
Ten
thousand.”

“Forget it, Logan,” spoke up Shein. “I’m not gonna buy a piece of that problem. No way I’m gonna put restrictions on her.”

“Look,” pressed Logan, “all I want is enforcement of the existing regulations limiting laypersons’ access to—”

“I told you, Logan, enough!” Shein’s hand came crashing down, sending papers flying. “What the hell’s wrong with you, whining at me like some kid starting med school?
You think you’re the first doctor who ever had some nasty little bureaucrat up his ass? Deal with it!”

Logan was bristling, but he tried hard not to let it show. “Don’t worry. I will.”

“Good. Now get out. If there’s one thing I can’t stand it’s a whiner.”

The younger man was stunned. Erratic as he was, Shein had never before addressed with him such frank contempt. He turned to leave, then stopped at the door. “I really don’t know what your problem is.”


My
problem? Lemme tell you something, Logan. You show me some results—then maybe you can ask me for favors.”

“What are you talking about? We only started administering the drug five weeks ago! Judy Novick was—”

“Forget her, the woman’s a goner! What’re you gonna do, haul her corpse around to show what a great job you’re doing?”

“Dr. Shein, that’s not—”

“How much time you think you got? In case you haven’t heard, people around this place aren’t known for their patience. A lotta drugs, they would’ve shown activity by now.
Convincing
activity.”

“We’re exactly at the same stage as Stillman’s protocol.”

“You think you’re Stillman? You think you got his options? Or his friends?”

Logan stared at him. So that was it—Shein wanted it both ways: credit if Compound J succeeded, but an escape hatch if it bombed out. He’d of course always known that, much as he relished the role of unbridled maverick, Shein was nearly as political as the rest. Yet never before had the fact been so nakedly obvious.

Shein picked up the disillusionment in the younger man’s look and caught himself. “Look, Logan, it’s not that I don’t understand your problem. Sure, Winston’s out to get you. It’s a good bet every vicious little thought that crosses her brain goes straight to the bad guys.”

“I’ll bet,” Logan concurred, although, in fact, the thought had never before occurred to him.

“But what I’m telling you—and there’s no better advice I can give—is stay focused on the big picture. Get results and no one’ll be able to fuckin’ touch you!”

“I’ll bear it in mind. We cure cancer and we’re home free.”

“Screw that self-pitying crap! You’d better pick up a lot more arrogance if you’re gonna make it in this business.”

“Don’t worry,” replied Logan. “Whatever has to be done to protect this protocol, I’ll do myself.”

“Oh, yeah?” Shein was suddenly interested. “Like what?”

“I’ve already arranged that from now on all our contacts with Winston’s office will be through Dr. Como. Neither Reston nor I will be dealing at all with any patient in the program with whom that maniac has any influence.”

“How many is that?”

“At least half of them.”

Going in, he’d hoped this would force the senior man’s hand; since, in leaving Sabrina with a far heavier workload than either of her associates, such an arrangement could disrupt the mechanics of a protocol in which Shein too—or so he’d thought—had a proprietary interest.

But Shein only smiled. “That’s what really gets to you, isn’t it? That she shows you up in front of that hot little number of yours.”

Abruptly, Logan forgot about concealing his anger. “You know something, Dr. Shein—”

“Seth.”

“—Dr
.
Shein
. Sometimes you’re as big an asshole as anyone around here!”

“Well, so much for all that famous gratitude of yours.” He grinned. “If I were you, Logan, I’d worry about keeping me
your
asshole.”

2 October 1930    
Frankfurt
             

Version #452 of compound a terrible disappointment. A gray mass, unable to recrystallize. All modifications in length of molecule have also failed! Deeply frustrated. Fear Herr Thomas is losing patience with this work
.

Could it be after all this time that synthetic approach is incorrect? Almost too horrifying to consider!

Emma supportive as ever, but my moods cannot be easy
. So
many detractors! So much pettiness among rivals! Where is the love of pure science?

Begin work tomorrow on version #453
.

 

L
ogan chose not to share with his colleagues the specifics of his exchange with Shein. What would be the point? Wouldn’t it only threaten the stability of an already fractured team? Anyway, he reassured himself, it was clear the senior man was exaggerating his qualms about Compound J for dramatic effect. Wasn’t overstatement—hell, shock value—the very essence of Shein’s style? The truth seemed self-evident: Shein had committed himself to the protocol publicly—and his senior colleagues would never let him forget it even if he wanted to.

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