The Autoimmune Connection: Essential Information for Women on Diagnosis, Treatment, and Getting On With Your Life (67 page)

Steatorrhea,
274

Steen, Virginia D.,
130
,
138
,
146
,
148

Stelara (ustekinumab),
158
,
256

Stem cell transplantation,
142–43
,
310
,
342

Step therapy,
453

Steroid sparing agents,
385

Steroids.
See
Corticosteroids

StrAbs.
See
Anti-striational muscle antibodies (StrAbs)

Streptomycin,
326
,
337

Stress reduction,
47

Subacute cutaneous lupus erythematosus,
67

Substance P,
419
,
424

Sugar Twin,
209

Sulfamethoxazole,
379

Sulfasalazine (Azulfidine)

Crohn’s disease,
251

pregnancy,
259

rheumatoid arthritis (RA),
38
,
51

ulcerative colitis,
264
,
265

Sulfonamides,
381

Sullivan, David A.,
175
,
183
,
186

Support groups,
457
,
465–75

Suppressor T cells,
5

Suprefact,
433

Sweet’N Low,
209

Symmetric PsA,
152

Symptoms,
16

Synarel,
433

Syndrome of primary biliary cirrhosis,
408

Synovectomy,
44

Synovial membrane,
23

Synovitis,
422

Synthroid,
111
,
410

Systemic lupus erythematosus (SLE),
63–98

apoptosis,
66

at-risk mothers,
90–92

breastfeeding,
87–89

cardiovascular disease,
94

cause,
65–68

diagnosis,
70–75

discoid lupus,
64
,
69
,
72
,
74
,
81

distinguishing features,
70–71

drug triggers,
68

drugs/medications,
77–81

estrogen,
92–93

female factor,
82–83

first-hand account (Deanna),
63
,
68–69
,
81–82
,
95–96

first-hand account (Jane),
74–75

genetic defects,
67

immune complexes,
66–67

laboratory tests,
71–75

lupus clusters,
81

lupus flare,
75–77

lupus fog,
69

lupus nephritis,
67
,
80
,
95

menopause,
93–94

menstruation,
83

neonatal lupus,
89–90

osteoporosis,
95

pregnancy,
84–90

race and ethnicity,
70

skin rashes,
69

symptoms,
69–70

warning signs,
65

Systemic sclerosis (SSc),
127
.
See also
Scleroderma

Systemic vasculitis,
380

T (thymine),
9

T cells,
4–6

T-score (DEXA),
278

T3.
See
Triiodothyronine (T3)

T4.
See
Thyroxine (T4)

Taclonex,
155

Tacrolimus,
156
,
265
,
335
,
401
,
403

Tadalafil,
140
,
142

Tagamet,
37
,
140
,
379

Takayasu’s arteritis,
381
,
383

Tapazole (methimazole),
111–12

Tazarotene (Tazorac),
155

Tcelna,
310

Teaching hospitals,
443

Team effort (physician-patient relationship),
448–50

Tear film layers,
174

Tecfidera,
306
,
452

Tegretol (carbamazepine),
308

Telangiectasias,
132

Temovate (clobetasol),
155

Temporal arteritis,
380
.
See also
Giant cell arteritis (CGA)

Temporomandibular joint (TMJ) syndrome,
420

Tender points (fibromyalgia),
417

Tenormin (atenolol),
114

Tensilon (edrophonium chloride),
329
,
332

Teriflunomide (Aubagio),
305–6

Teriparatide,
58
,
230

Terminal ileum,
240

Testosterone,
15
,
115
,
299

Tetany,
229

Tetracycline,
254
,
337

Th1 cells,
5

Th2 cells,
5

Th17 cells,
5

Thalidomide (Thalomid),
81
,
257
,
267

Thera Tears,
184

Thera Tears Nutrition,
186

Thrombin,
348

Thrombocytopenia,
67
,
71
,
353
,
362
.
See also
Immune thrombocytopenia (ITP)

Thrombocytopenic purpura,
366

Thrombopoietin (TPO),
365

Thrombopoietin receptor agonists,
373

Thunder god wine,
45

Thymectomy,
326
,
331
,
332

Thymic abnormalities,
323

Thymoglobulin,
214

Thymoma,
323
,
333

Thyroglobulin (TG),
102
,
108

Thyroid antibody blood tests,
108

Thyroid autoantibodies,
102

Thyroid-binding globulin (TBG),
118

Thyroid disease,
99–126

anatomy,
99–100

bone loss,
124

clusters,
117

diagnosis,
107–9

female factor,
115–16

fertility,
117–18

first-hand account (Anne Marie),
99
,
105
,
109

first-hand account (Lynne),
116

heredity,
103

laboratory tests,
107–9

later life,
122–24

menopause,
122

menstruation,
117–18

neonatal thyroid disease,
120

overactive thyroid.
See
Graves’ disease

postpartum thyroid disease,
120–21

postpartum thyroiditis,
115

pregnancy,
118–20

thyroid feedback loop,
100
,
101

underactive thyroid.
See
Hashimoto’s thyroiditis

warning signs,
101

Thyroid disease clusters,
117

Thyroid feedback loop,
100
,
101

Thyroid gland,
99
,
100

Thyroid scan,
109

Thyroid stimulating antibodies,
102

Thyroid stimulating hormone (TSH),
100

Addison’s disease,
226

immune thrombocythemia (ITP),
369

pregnancy,
118
,
119

Sjögren’s syndrome,
180–81

thyroid function,
108

Thyroid stimulating immunoglobulins,
102

Thyroid storm,
105

Thyroidectomy,
113

Thyroperoxidase (TPO),
102
,
108

Thyrotropin receptor antibody (TPO),
102

Thyrotropin releasing hormone (TRH),
100

Thyroxine (T4),
100
,
108

TIA.
See
Transient ischemic attack (TIA)

Tiazac,
139

Tirasemtiv,
342

Tizanidine (Zanaflex),
308

TLRs.
See
Toll-like receptors (TLRs)

TMJ syndrome.
See
Temporomandibular joint (TMJ) syndrome

TNFα,
430
.
See
Tumor necrosis factor alpha (TNFα)

TNFα blockers.
See
Tumor necrosis factor alpha (TNFα) blockers

Tocilizumab (Actemra),
10
,
40
,
51
,
256

Tofacitinib (Xeljanz),
10
,
41
,
165
,
166
,
256

Tofranil (imipramine),
308

Toll-like receptors (TLRs),
82

Topical sensitizers,
165

Topiramate (Topamax),
189

Total thyroxine (T4),
108

Total triiodothyronine (T3),
108

TOUCH prescribing program,
304

Toujeo,
206

TPO.
See
Thrombopoietin (TPO)

TRAbs,
108
,
124

Tracleer (bosentan),
141

Tramadol,
424

Transient ischemic attack (TIA),
349

Transitional MS,
296

Treat to target,
35

Tregs,
5

Trental (pentoxifylline),
139

Treprostinil,
142

Tretinoin,
157

Trexall,
38
.
See also
Methotrexate (MTX)

TRH.
See
Thyrotropin releasing hormone (TRH)

Trigeminal neuralgia,
294

Triiodothyronine (T3),
100
,
108

Trimesta,
300

Tripterygium wilfordii Hook F (TwHF),
45

Truvia,
209

TSH.
See
Thyroid stimulating hormone (TSH)

TSH inhibiting antibodies,
120

tTG,
273

tTG IgA,
277

Tumor necrosis factor alpha (TNFα,
6
,
10
,
158
,
188
,
381
,
430

Tumor necrosis factor alpha (TNFα blockers,
153
,
158
,
252–53
,
386
,
395

Turner, Kathleen,
22
,
28
,
30–31
,
34–35
,
48
,
58
,
450
,
458

Turner’s syndrome,
231

25-hydroxyvitamin D [25(OH)D],
292

TwHF.
See
Tripterygium wilfordii Hook F (TwHF)

Type 1 APS,
227
,
228

Type 1 diabetes,
195–221

artificial pancreas device system (APDS),
212–13

cause,
197–99

clusters,
212

DCCT,
205–6

diabetic dermopathy,
202

diabetic ketoacidosis,
200

diabetic nephropathy,
202

diabetic retinopathy,
201

diagnosis,
202–5

diet,
209–10

fertility,
215–17

first-hand account (Mary Kay),
195
,
199–200
,
205
,
212
,
219

glucose self-monitoring,
208–9

hyperglycemia,
200

hypoglycemia,
210–11

insulin,
206–8

laboratory tests,
203–4

menopause and beyond,
219–21

menstruation,
215–17

MS,
11

pregnancy and lactation,
217–19

race and ethnicity,
197

symptoms/complications,
200–202

treatment,
205–14

warning signs,
197

Type 1 diabetes clusters,
212

Type 2 APS,
227
,
228

Type 2 diabetes,
196
,
197

Type 3 APS,
227
,
228

Tysabri (natalizumab),
254
,
304

UAS.
See
Undifferentiated autoimmune syndrome (UAS)

UC.
See
Ulcerative colitis (UC)

UCTD.
See
Undifferentiated connective tissue disease (UCTD)

UDCA.
See
Ursodeoxycholic acid (UDCA)

Ulcer,
131

Ulcerative colitis (UC),
261–70

cause,
261

colon cancer,
267–68

diagnosis,
262–63

disease activity classifications,
263
,
264

fertility,
268

laboratory tests,
262–63

midlife and beyond,
269

reproduction,
268–69

symptoms,
261–62

treatment,
263–67

warning signs,
241

Ulcerative jejunitis,
281

Ulcerative proctitis,
262

Ultravate,
155

Ultraviolet light A (UVA),
156

Ultraviolet light B (UVB),
156

Underactive thyroid.
See
Hashimoto’s thyroiditis

Undifferentiated autoimmune syndrome (UAS),
136

Undifferentiated connective tissue disease (UCTD),
136

Upper endoscopy with small bowel biopsy,
277

Upper GI series,
136
,
248

Urine dipstick test,
74

URSO 250,
409
.
See also
Ursodiol

URSO Forte,
409
.
See also
Ursodiol

Ursodeoxycholic acid (UDCA),
409

Ursodiol,
410
,
411

Urticarial vasculitis,
382

Ustekinumab (Stelara),
158
,
256

Uveitis,
152
,
246

Vagifem,
53
,
191