The Lucky Years: How to Thrive in the Brave New World of Health (44 page)

medications in,
76
–78

Preventive Services Task Force, US,
181
,
216

Prilosec (omeprazole),
86

Princeton University,
17

Principles and Practice of Medicine, The
(Osler),
71
,
72

probiotics,
35
,
35
,
36

Proceedings of the National Academy of Sciences,
46
,
95

processed foods,
121
,
142

prolactin,
211

prostate,
154

prostate cancer,
93
,
166
–69,
171
,
190
,
211
,
217

active surveillance approach to,
166
–67

statin use and,
219

proteins,
139

proteomics,
83
–84,
88

proton pump inhibitors (PPIs),
86

PSA (prostate-specific antigen),
167
–68

public health,
233
–34

PubMed,
178

quality of life,
128

Queensland, University of,
41

radiation therapy,
29
,
60

“rapid cognition,”
227

Reading, University of,
134

receptors,
30
,
59

rectal cancer,
see
colorectal cancer

red blood cells,
231

red meat,
162

life span and,
142
–43

processed,
142
,
143

Reid, Ian,
181

Reifler, Jason,
157

reproductive maturity,
41

Reprogenetics,
112

research papers, overlooked and forgotten,
94
–95

retirement, health and,
91
–92

rickets,
180

RNA (ribonucleic acid),
139

Robb, Hunter,
72

Rochester, University of, Center for Translational Neuromedicine at,
208

Rogozov, Leonid,
94

Romania,
212
–13

Rostock,
41

Royal Air Force,
108

Royal Society,
100

Saint, The—Johns Hopkins Hospital
(Broedel),
73

Saint Barnabas Medical Center,
111

St. Pancras,
161

saline solution,
234

Salk Institute for Biological Studies,
138

San Diego, Calif.,
211

San Diego State University,
138

Sandy, Hurricane,
84

San Francisco, Calif.,
166

San Francisco Giants,
205

sanitation,
234

Sanofi,
117

sarcopenia,
195
–96

satiety,
122

saw palmetto,
154
–55,
168

Science,
14
,
37
,
84
,
95
,
102
,
123
–24,
138
,
169

Scripps Translational Science Institute,
114
–15

security, of medical databases,
88
–89

selenium,
169

Selenium and Vitamin E Cancer Prevention Trial (SELECT),
169

senility, aging and,
44

September 11, 2001, terrorist attacks of,
103

sex,
210
–12

Shakespeare, William,
1
,
202

shingles,
161

single-nucleotide polymorphisms (SNPs),
113
–14

sitting,
186
–87,
190
,
192
–93

“16 Decisions,”
234
,
235

sleep,
146
–48,
202
–10

apps for tracking,
147
–48

hormone balance and,
207

microbiome and,
122
–23

sleep apnea,
202
–4,
203

sleep deprivation,
202
–10

chronic disease and,
205

and sports performance,
204
–5

sleep disorders,
202
–6

“sleeping beauties,” research papers as,
94
–95

sleep ranges,
206
–7

sleep-wake cycle,
140

Sloan Kettering Institute,
58
,
62

smallpox,
160

Smallpox and Inoculation Hospital,
161

smartphones, health care and,
79
,
90

smoking,
22
,
47
,
57
,
171
,
176
–77,
186
,
188
,
237

snoring,
203
,
207

social deprivation,
213

Southern Denmark, University of,
41

Soviet Union,
94

soy,
168

Spain,
58

Sports Illustrated,
202

squamous cell lung cancer,
118

Stanford University,
3
,
23
,
44
,
63
,
86
,
178

State of the Union address (2015),
114

statins,
76
,
77
–78,
93
,
136
,
217
–22

Stein, Fred,
28

stem cells,
170
,
171
,
176
,
201

differentiation in,
63

male vs. female,
64

reactivation of,
4
,
5

in research,
63
–64

strength training,
194

stress,
22
,
137
–38,
211

honesty about,
133
–34

among Romanian children,
213

strokes,
76
,
128
,
182
,
217
,
218

sub-Saharan Africa,
77

sugar consumption, honesty about,
134

supplement industry, lack of regulation in,
19

supplements,
145
,
153
,
154
–55,
182

Surgeon General, US,
137

surrogate markers,
127
–28

SWOG cancer research cooperative group,
169

symptoms, unexplained,
146

tamoxifen,
53

Tanzania,
163

T cells,
29
–30,
56

engineered,
57

TCP-1 ring complex chaperonin,
139
–40

technology:

ethics and,
25
–26

health and,
37
–70

inflection points in,
7
–8,
7

lack of oversight of,
9

population growth and,
27

teixobactin,
68
–69

telemedicine,
80
–81

telomeres,
64
–65

Tempest, The
(Shakespeare),
1

Tennessee, University of,
23

testosterone,
200
–201

Texas,
103

TGF-beta (transforming growth factor beta),
58
–59

“thin-slicing,”
227

3-D printing, medications and,
66
–67

thyroid cancer,
93

tobacco,
177
,
237

Tomasetti, Cristian,
169
–70,
171
–72

Topol, Eric,
114
–15

touch,
212
–15

Touch: The Science of Hand, Heart, and Mind
(Linden),
215

Touch Research Institute (University of Miami’s Miller School of Medicine),
214

trastuzumab (Herceptin),
55

triglyceride level,
150
,
195

True, Marion,
226
–27

tumors, sequencing of,
49
–52,
50
,
51
,
54
,
61
,
113
,
114

Turnbull, Douglass,
108
–9

Turner’s syndrome,
112

turquoise killifish,
44
–45,
44

two-week challenge,
126
–52

chronological age and,
135
–36

energy levels in,
149

exercise in,
148

habits and routines in,
137
–41

heritage and family history in,
136
–37

medications and management of conditions in,
144
–46

mood and motivation in,
149

sleep needs in,
146
–48

weight and diet in,
141
–44

Ukraine,
33

“Underappreciated Role of Muscle in Health and Disease, The” (Wolfe),
194

United Kingdom,
134
,
219
,
220

see also
Great Britain

United States, leading causes of death in,
129

University of Arkansas for Medical Sciences, Center for Translational Research in Aging and Longevity at,
194

Utah,
47

vaccines:

autism spectrum disorders and,
18
,
153
,
155
–56

public distrust of,
160
–61

universal innoculation and,
160
–61

vagus nerve,
122

Vanderbilt University Medical Center,
204

Veasey, Sigrid,
208
,
210

vincristine,
115

Virginia,
204

Virginia, University of,
37
,
214

Virginia Tech shooting,
91

VirScan,
84
–85

viruses,
84
–85,
119

data mining and,
85

human genome and,
119
–20

vitamin A deficiency,
235

vitamin D,
179
–81

vitamin E,
168
–69

vitamins,
145
,
153
,
182

Vogelstein, Bert,
169
–70,
171
,
172

Wakefield, Andrew,
155

Walker, Jay,
98
–99

Walker Library of the History of Human Imagination,
98
–99

Walmart,
221

Washington Post,
88

Watson (IBM supercomputer), cancer treatment and,
88
–89

weight, diet and,
141
–42

Wellcome Trust Centre for Mitochondrial Research,
108

wellness checkups,
78
–80

Western Africa,
222

West Nile virus,
25

West Virginia,
47

whooping cough,
160

“Why Most Published Research Findings Are False” (Ioannidis),
178

Wikipedia, medical misinformation on,
154

Winter, Christopher,
204
–5

Wolfe, Robert,
194

women, microfinancing and,
233
–34

World Economic Forum,
161
–62,
166

World Health Organization (WHO),
67
,
170
,
187
,
188

World Series (2014),
205

X chromosome,
63
–64

Yale Law School,
159

Y chromosome,
63
–64

yogurt,
34

Yunus, Muhammad,
232
–35

Zaltrap (aflibercept),
117

Zeri, Federico,
226

Zykadia (ceritinib),
53

Simon & Schuster

1230 Avenue of the Americas

New York, NY 10020

www.SimonandSchuster.com

Copyright © 2016 by Dr. David B. Agus

All rights reserved, including the right to reproduce this book or portions thereof in any form whatsoever. For information address Simon & Schuster Subsidiary Rights Department, 1230 Avenue of the Americas, New York, NY 10020.

First Simon & Schuster hardcover edition January 2016

SIMON & SCHUSTER and colophon are registered trademarks of Simon & Schuster, Inc.

For information about special discounts for bulk purchases, please contact Simon & Schuster Special Sales at 1-866-506-1949 or
[email protected]
.

The Simon & Schuster Speakers Bureau can bring authors to your live event. For more information or to book an event contact the Simon & Schuster Speakers Bureau at 1-866-248-3049 or visit our website at
www.simonspeakers.com
.