The Lucky Years: How to Thrive in the Brave New World of Health (40 page)
Read The Lucky Years: How to Thrive in the Brave New World of Health Online
Authors: David B. Agus
22
. S. F. Nielsen, B. G. Nordestgaard, and S. E. Bojesen, “Statin Use and Reduced Cancer-Related Mortality,”
New England Journal of Medicine
367, no. 19 (November 8, 2012): 1792–802, doi:10.1056/NEJMoa1201735. Also see S. F. Nielsen, B. G. Nordestgaard, and S. E. Bojesen, “Statin Use and Reduced Cancer-Related Mortality,”
New England Journal of Medicine
368, no. 6 (February 7, 2013): 576–77, doi:10.1056/NEJMc1214827.
23
.
C. R. Cardwell et al., “Statin Use and Survival from Lung Cancer: A Population-Based Cohort Study,”
Cancer Epidemiology, Biomarkers & Prevention
24, no. 5 (May 2015): 833–41, doi:10.1158/1055-9965.EPI-15-0052.
24
. Leah Lawrence, “Statins Linked with Reduced Liver Cancer in Low-Rate Areas,” Cancer Network, March 19, 2015,
www.cancernetwork.com/gastrointestinal-cancer/statins-linked-reduced-liver-cancer-low-rate-areas#sthash.mYYAMgXP.dpuf
.
25
. L. C. Harshman, “Statin Use at the Time of Initiation of Androgen Deprivation Therapy and Time to Progression in Patients with Hormone-Sensitive Prostate Cancer,”
JAMA Oncology
1, no. 4 (July 1, 2015): 495–504, doi:10.1001/jamaoncol.2015.0829.
26
. C. R. Cardwell et al., “Statin Use After Colorectal Cancer Diagnosis and Survival: A Population-Based Cohort Study,”
Journal of Clinical Oncology
32, no. 28 (October 1, 2014): 3177–83, doi:10.1200/JCO.2013.54.4569, Epub August 4, 2014.
27
. T. J. Murtola et al., “Statin Use and Breast Cancer Survival: A Nationwide Cohort Study from Finland,”
PLOS ONE
9, no. 10 (October 20, 2014): E110231, doi:10.1371/journal.pone.0110231. eCollection 2014.
28
. A. Pursnani et al., “Guideline-Based Statin Eligibility, Coronary Artery Calcification, and Cardiovascular Events,”
Journal of the American Medical Association
314, no. 2 (July 14, 2015): 134–41, doi:10.1001/jama.2015.7515.
29
. J. M. Patel et al., “Randomized Double-Blind Placebo-Controlled Trial of 40 Mg/Day of Atorvastatin in Reducing the Severity of Sepsis in Ward Patients (ASEPSIS Trial),”
Critical Care
16, no. 6 (December 11, 2012): R231, doi:10.1186/cc11895. For an intriguing commentary on this phenomenon, see David S. Fedson and Steven M. Opal, “Can Statins Help Treat Ebola?,”
New York Times
, August 15, 2014.
1
. Malcolm Gladwell,
Blink: The Power of Thinking Without Thinking
(New York: Little, Brown, 2005).
2
. Excerpt from Gladwell,
Blink: The Power of Thinking Without Thinking
, iBooks.
https://itun.es/us/wByuv
.
3
. Michael Kimmelman, “ART; Absolutely Real? Absolutely Fake?,”
New York Times
, August 4, 1991.
4
. Charles Duhigg,
The Power of Habit: Why We Do What We Do in Life and Business
(New York: Random House, 2012).
5
. For a comprehensive review of perceptual intuition, see Benedict Carey, “Brain Calisthenics for Abstract Ideas,”
New York Times
, June 6, 2011. Also see Carey, “Learning to See Data,”
New York Times
, March 27, 2015.
6
.
To learn more about Muhammad Yunus and his work, visit the Yunus Center’s website at
http://muhammadyunus.org
.
7
. To read Lorenz’s original academic paper, go to
http://eaps4.mit.edu/research/Lorenz/Butterfly_1972.pdf
.
8
. J. Lightwood and S. A. Glantz, “The Effect of the California Tobacco Control Program on Smoking Prevalence, Cigarette Consumption, and Healthcare Costs: 1989–2008,”
PLOS ONE
8, no. 2 (2013): E47145, doi:10.1371/journal.pone.0047145, Epub February 13, 2013.
9
. Federal Trade Commission. Federal Trade Commission Cigarette Report for 2012.
10
. “Youth and Tobacco Use,” Centers for Disease Control and Prevention, last modified July 24, 2015,
www.cdc.gov/tobacco/data_statistics/fact_sheets/youth_data/tobacco_use/index.htm
.
11
. Aldous Huxley,
Brave New World
(New York: Random House, 1932), chap. 17.
A note about the index:
The pages referenced in this index refer to the page numbers in the print edition. Clicking on a page number will take you to the ebook location that corresponds to the beginning of that page in the print edition. For a comprehensive list of locations of any word or phrase, use your reading system’s search function.
Page numbers in
italics
refer to illustrations.
acute lymphoblastic leukemia,
115
adenocarcinomas,
216
Advil,
66
“Aequanimitas” (Osler),
75
Affordable Care Act,
69
–70
aflibercept (Zaltrap),
117
age:
chronological,
45
,
46
,
46
,
47
,
135
–36,
232
coarse-graining in,
231
–32
context and,
45
feebleness and,
43
fertility and,
43
immune system and,
44
in males vs. females,
63
–64
mortality rates and,
42
–43
muscle loss in,
195
–96
in other species,
41
–45
parabiosis experiments on,
1
–4,
3
,
21
plasma transfusions and,
4
–5
senility and,
44
telomeres and,
64
–65
theories of,
40
–41
AIDS,
see
HIV/AIDS
airport noise, cardiovascular disease and,
92
Alabama,
47
alcohol abuse,
22
Alzheimer’s disease,
5
,
8
,
10
,
91
,
108
,
113
,
118
,
129
,
163
,
175
,
203
–4,
215
diet and,
163
American College of Cardiology,
218
American Heart Association,
183
,
218
American Institute for Cancer Research,
190
American Journal of Clinical Nutrition,
194
amino acids,
194
Amsterdam, University of,
41
amyotrophic lateral scleroris (ALS),
119
–20
Angell, Marcia,
178
Annals of Internal Medicine,
181
Anopheles
mosquito,
77
Antarctica,
94
antiaging drugs,
201
antiaging hoaxes,
200
–201
antibiotics,
145
appendicitis and,
94
antibodies,
84
–85
antidepressants,
145
antioxidants,
208
antivaccine movement,
155
–56
anxiety,
122
apoptosis,
59
appendicitis,
93
–94
Archives of Internal Medicine,
142
,
143
,
192
,
196
Arizona State University,
134
artificial sweeteners,
85
–86,
120
Asia,
77
anticancer qualities of,
216
–17
Associated Press,
21
asthma,
59
Athens,
226
atherosclerosis,
183
ATP (adenosine triphosphate),
107
Auckland, University of,
181
Aurora shooting,
81
Autier, Philippe,
180
–81
autism spectrum disorders,
108
,
112
autoimmune diseases,
85
,
125
,
175
Avastin (bevacizumab),
11
Ayurveda,
113
bacteria:
beneficial,
33
–34
as earth’s first inhabitants,
124
bacterial sepsis,
222
balance,
45
Baltimore, Md.,
74
Bang, Hans Olaf,
182
–83
Bangladesh,
232
–35
Beaverton, Oreg.,
109
Benda, Carl,
107
Bernardi, Edward,
104
–5
Bernardi, Sharon,
104
–6,
108
–9,
111
bevacizumab (Avastin),
11
Big Data,
see
databases, medical; data mining
Big Pharma,
see
pharmaceutical industry
Bill & Melinda Gates Foundation,
87
Bills of Mortality,
96
,
97
–99,
98
,
99
,
100
biopsies, blood-based,
61
blastocysts,
109
Blink: The Power of Thinking Without Thinking
(Gladwell),
225
blood-brain barrier,
54
blood clotting,
187
blood pressure,
22
,
47
,
188
,
195
,
218
range of,
136
blood sugar levels,
151
body:
resilience of,
49
“self” vs. “nonself” in,
34
body mass index (BMI),
22
,
134
,
141
Boston, Mass.,
84
Boston Cooking-School Cook Book, The,
178
Boston University,
47
Bowerman, Bill,
199
brain:
decision making in,
227
sleep’s importance to,
208
–10
brain cancer,
30
Brave New World
(Huxley), viii,
159
,
238
Brazil,
199
breast cancer,
8
,
53
,
55
,
60
,
61
,
118
,
171
,
190
,
211
genetic mutation and,
21
–22
mastectomies and,
21
–22
obesity and,
133
statin use and,
220
Breast Cancer Prevention Trial,
53
Brigham and Women’s Hospital,
84
Broad Institute of MIT and Harvard,
23
,
24
Broedel, Max,
73
Brown University,
58
Brunet, Anne,
63
bubonic plague,
95
–101
Bulletin of the New York Academy of Medicine,
2
butterfly effect,
236
–37
tobacco control program in,
237
California, University of:
at Berkeley,
25
at Irvine,
3
at San Francisco,
3
Caltech,
102
Cambridge, University of,
125
,
134
Cameron, David,
67
aggressiveness of,
53
–54
alternative treatments for,
18
aspirin and,
216
–17
chemotherapy for,
29
context and,
13
–14
diet and,
163
early detection and treatment of,
172
fitness and,
190
–94